Angiotensin-Converting Enzyme Gene Polymorphism and Carotid Artery Wall Thickness
نویسندگان
چکیده
منابع مشابه
Angiotensin-converting enzyme gene polymorphism and carotid artery wall thickness: a meta-analysis.
BACKGROUND AND PURPOSE Many studies have investigated the association between the angiotensin-converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism and carotid artery intima-media thickness (IMT); however, most studies were small and conducted in selective samples. The aim of this study was to evaluate this association by performing a meta-analysis on published articles. METHODS ...
متن کاملAngiotensin-converting enzyme gene polymorphism and carotid wall thickening in a community population.
The insertion/deletion (I/D) polymorphism of the angiotensin-converting enzyme (ACE) gene has been associated with an increased risk of coronary heart disease, but whether it is a risk factor for underlying atherosclerosis remains unclear. Therefore, we examined to see whether the ACE gene deletion polymorphism was associated with carotid wall thickening and atherosclerotic plaque formation in ...
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Background Mechanisms underlying the previously reported association between a deletion polymorphism in the gene encoding for angiotensin-converting enzyme (ACE) and the risk of myocardial infarction in low-risk subjects are unclear. The purpose of this case-control study was to examine the relation of plasma ACE activity to intimal-medial thickness of the carotid wall measured ultrasonographic...
متن کاملPlasma angiotensin-converting enzyme activity and carotid wall thickening.
BACKGROUND Mechanisms underlying the previously reported association between a deletion polymorphism in the gene encoding for angiotensin-converting enzyme (ACE) and the risk of myocardial infarction in low-risk subjects are unclear. The purpose of this case-control study was to examine the relation of plasma ACE activity to intimal-medial thickness of the carotid wall measured ultrasonographic...
متن کاملAngiotensin Converting Enzyme Gene Polymorphism in Iranian Patients with Type 2 Diabetes
Background: Angiotensin I converting enzyme (ACE) is a Zinc metalloproteinase, converts Ang-I to Ang- II, a pro-inflammatory agent which may contribute to pathophysiology of some diseases like type 2 diabetes. Objective: To investigate the relationship between ACE I/D polymorphism and type 2 diabetes in 261 Iranian casecontrol pairs. Methods: 170 patients (85 type 2 diabetics with nephropathy a...
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ژورنال
عنوان ژورنال: Stroke
سال: 2003
ISSN: 0039-2499,1524-4628
DOI: 10.1161/01.str.0000077926.49330.64